Authors present a study on the human-induced landscape of fear in brown bears, which is an extremely important issue as human persecution is a major cause of mortality for large carnivores. Large carnivores avoid humans, but may use human-dominated landscapes by being nocturnal and elusive. Behavioral studies indicate that certain ecological systems are “landscapes of fear”. Because behavior and physiology are closely interrelated, physiological assessments may provide insight into the behavioral response of large carnivores to human activity.